Quote of the Day

The embarrassing truth about clinical work with antidepressants was that it was all art and no science. Various combinations of symptoms were said to be more serotonin- or norepinephrine-related, and various strategies were advanced for trying medications in logical order for particular sorts of patients. But these strategies varied from year to year, and even from one part of the country to another. It was true that a given patient might respond to one antidepressant after having failed to respond to another, but the doctor would have to manufacture a reason to explain why. [Kramer, Peter D., Listening to Prozac (Penguin Books, 1997), p. 59]